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In conclusion, heme–HPX, which regulates cell iron homeostasis and proliferation/cell growth, is taken up by clathrin-mediated endocytosis and raises intracellular ferrous iron safely for the IRE/IRP system of translational regulation
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Then, the cells were washed twice with Hank's balanced salt solution (HBSS) and incubated with dihydroethidium (DHE
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