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A brand new study looked at glycine and NAC (research here) effect on BDNF for older people: GlyNAC could also be having a direct effect in the brain as seen by a significant increase in the diminished levels of the brain biomarker BDNF The results of allowing this to drop as we get older (see CBD and dementia): DNF is involved in the preservation of memory, synaptic plasticity, and maintenance of neuronal networks,64, 65 and lower plasma levels of BDNF are associated with lower cognitive test scores and mild cognitive impairment