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Glucocorticoids plus N-Acetylcysteine in Severe Alcoholic Hepatitis | New England Journal of Medicine

Although nonlinear dose–exposure relationships cannot be excluded for an endogenously regulated analyte, the higher exposure observed with LipoMicel ® relative to both a higher-dose standard formulation and a dose-matched liposomal formulation supports a formulation-dependent contribution to systemic glutathione delivery

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Overall, we found that CAR T cells in post-infusion BM samples from LTR have high levels of mTOR signaling, high metabolic polyfunctionality, and an effector immunometabolic profile, and that the BM microenvironmental milieu of LTR may promote mTOR activity for improved anti-tumor activity

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