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Cryptococcus neoformans adapts to host CO2 concentrations via metabolic and stress-response remodeling | PLOS Biology
Specifically, the accumulation of oxidized low-density lipoprotein (oxLDL) in Mφs enhanced LPS-induced expression of NRF2-dependent ROS detoxification enzymes (i.e., GSR) and suppressed the expression of HIF-1α-dependent ROS producing enzymes (i.e., NOS2)
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