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Inactivation of DHODH in cancer cells with low GPX4 expression significantly increased intracellular lipid peroxidation, while in cancer cells with high GPX4 expression, DHODH inactivation synergized with inducers to enhance ferroptosis
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If b12 deficiency exists and causes fatigue that limits physical activity, correcting the deficiency may indirectly support weight loss by enabling more movement
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