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In aqueous solution the dominant degradation routes reported for short peptides are hydrolysis of labile amide bonds, oxidation of methionine and tryptophan residues, and deamidation at asparagine and glutamine residues, all of which accelerate with temperature, repeated freeze-thaw cycling and exposure to light

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[DOI] [PMC free article] [PubMed] [Google Scholar] [119].Tessema B, Sack U, König B, Serebrovska Z, Egorov E (2022)