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Replying to @Shayan khan BPC 157 the crazy healerโฆ? ๐ค๐ค๐ค Surprisinglyโฆyes. Or at least it seems to be based on the current available evidence. One of my sponsors, Transcend even carries it, however I ...
First, it interacts with electrophilic groups and scavenges free radicals such as hydrogen peroxide and superoxide with the help of its thiol side chain [7,9]
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GLP-RT Quantity:15mg
Documented effects include: Upregulation of SOD1 (cytosolic Cu/Zn-SOD), CAT (catalase), and GPX1 (glutathione peroxidase 1) mRNA and protein in multiple cell types NRF2 nuclear translocation and ARE-driven gene induction (HO-1, NQO1, GCLC, TXNRD1) Reduction of 4-hydroxynonenal (4-HNE) adducts and 8-hydroxy-2โฒ-deoxyguanosine (8-OHdG) โ markers of lipid peroxidation and oxidative DNA damage respectively Mitochondrial ROS reduction via Complex IV cuproenzyme enhancement (cytochrome c oxidase activity assay) Epitalonโs antioxidant activity is primarily documented via melatonin restoration (melatonin is itself a potent radical scavenger) and through modest upregulation of SOD and catalase in aged rodent tissues โ a secondary effect rather than a primary mechanism
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