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Cancer cells appear to undergo a tissue-specific metabolic rewiring, which converges toward a common metabolic landscape
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PPP involves the formation of a bypass from glucose-6-phosphate, an intermediate product of glycolysis, which produces fructose-6-phosphate and glyceraldehyde-3-phosphate through two stages of oxidation and group transfer back to glycolysis, also referred to as the hexose monophosphate shunt
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