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The loss of Grx2 function also led to the activation of iron regulatory protein (IRP1), resulting in the increase in the iron uptake protein transferrin receptor, decreased levels of the iron storage protein ferritin, and mitochondrial iron accumulation
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When considered separately, women exposed to high levels of ozone air pollution who were under 35 years of age had a 26% increase and those who had borne children had a 28% increase in fibroid risk (Wesselink 2021)
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