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If you are interested in the details behind what we have just discussed: First, sulfonamide antibiotics have a N4 arylamine group, which is an NH₂ group attached to an aromatic group.¹ ² Second, they have an N1 group, which is a 5-6 membered heterocyclic ring that contains one or more nitrogen within the ring.¹ ² These key differences are highlighted in the picture below
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[DOI] [PMC free article] [PubMed] [Google Scholar] [126].Formica C, Peters DJM, Molecular pathways involved in injury-repair and ADPKD progression, Cellular Signalling, 72 (2020) 109648
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