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Although these novel matrices may not completely replace the classical ones, the rational design of matrices with molecular recognition properties will extend the applicability of MALDI ionization mechanisms to a wider range of compounds and is expected to find new and interesting applications in targeted MALDI-MS or MALDI-MSI analysis
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2.3 Search strategy To identify all potentially relevant studies, a comprehensive literature search was carried out in the PubMed, Scopus, Web of Science, and Cochrane Library databases
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